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|
Variable
|
Experiment 1
|
Experiment 2
|
|---|
|
controls
|
db cAMP
|
controls
|
db cAMP
|
|---|
|
Hypothalamus
|
|
ADCYAP1
|
0.56±0.02
|
0.78±0.02*
|
0.41±0.02
|
0.59±0.02
|
|
GHRH#
|
0.51±0.04
|
1.39±0.05**
|
0.38±0.05
|
0.72±0.08*
|
|
CRH#
|
0.94±0.03
|
1.53±0.06*
|
0.66±0.02
|
0.97±0.05*
|
|
POMC
|
0.81±0.01
|
1.00±0.01*
|
0.46±0.03
|
1.81±0.01**
|
|
PC1#
|
0.33±0.02
|
0.80±0.05*
|
0.64±0.04
|
0.99±0.01*
|
|
PC2#
|
0.35±0.02
|
0.55±0.03
|
0.71±0.02
|
0.82±0.01
|
|
Pituitary gland
|
|
GHRHR#
|
0.72±0.01
|
0.95±0.01*
|
0.45±0.01
|
0.46±0.01
|
|
GH#
|
0.50±0.02
|
1.20±0.01**
|
0.39±0.01
|
0.84±0.03*
|
|
CRHR
|
0.59±0.03
|
0.62±0.03
|
0.59±0.01
|
0.75±0.08
|
|
POMC#
|
0.49±0.02
|
1.13±0.01*
|
0.42±0.01
|
0.82±0.01*
|
|
TRHR
|
0.51±0.01
|
0.58±0.03
|
0.39±0.02
|
0.53±0.01
|
|
TSH
|
1.44±0.04
|
1.49±0.02
|
0.66±0.04
|
0.88±0.03
|
|
Liver
|
|
GHR#
|
0.55±0.01
|
1.06±0.03**
|
0.86±0.01
|
0.93±0.05
|
|
IGF-1#
|
0.50±0.01
|
1.14±0.01**
|
0.57±0.01
|
1.10±0.02*
|
- Within stages, means with * differ (P < 0.05) and those with ** differ (P < 0.01).
- Within the same line, # means the effects of dbcAMP in experiment 1 is differ from experiment 2.
