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Table 1 Relative expression of genes (fold change, Chinese vs. Indian) involved in xanthophyll uptake and metabolism in prefrontal cortex (PFC), cerebellum (CER), and striatum (STR) of Indian and Chinese-origin rhesus monkeys (n = 3 per group)

From: Brain xanthophyll content and exploratory gene expression analysis: subspecies differences in rhesus macaque

  Fold change-PFC p value Fold change-CER p value Fold change-STR p value
BCO1 −1.15 0.77 2.75 0.99 1.84 0.37
BCO2 1.64 0.006 1.58 0.13 1.69 0.01
NPC1L1 1.54 0.34 −1.06 0.91 1.26 0.60
ABCG5 −1.37 0.99 1.17 0.68 1.06 0.91
ABCA1 1.05 0.84 −1.01 0.99 1.43 0.06
SCARB1 1.18 0.12 1.10 0.43 1.20 0.09
GSTP1 1.07 0.52 −1.09 0.59 1.15 0.38
STARD3 1.09 0.99 1.07 0.99 1.31 0.99
LIPC −1.61 0.25 1.38 0.99 −1.37 0.46
ELOVL2 −1.02 0.87 1.06 0.71 1.08 0.67
ELOVL4 1.25 0.04 1.06 0.66 1.11 0.50
ELOVL5 1.14 0.49 −1.05 0.81 1.24 0.29
FADS1 1.17 0.15 1.20 0.20 1.55 0.01
FADS2 1.16 0.12 −1.04 0.75 1.32 0.05
RPE65 −1.28 0.44 −2.44 0.03 −1.37 0.26
ALDH3A2 −1.11 0.26 −1.05 0.61 1.02 0.89
  1. Fold change calculated by dividing fragments per kilobase of transcript per million mapped reads (FPKM) Chinese origin by FPKM Indian origin. Genes in italics showed a significant difference in expression in at least one brain region. Genes in bold were selected for RT-PCR analysis
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Genes & Nutrition

ISSN: 1865-3499

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